Eckhard Wolf Selected Research

Juvenile gout

4/2014	No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.
1/2014	Uromodulin retention in thick ascending limb of Henle's loop affects SCD1 in neighboring proximal tubule: renal transcriptome studies in mouse models of uromodulin-associated kidney disease.
10/2013	Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice.
1/2013	Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice.
11/2009	Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Eckhard Wolf Research Topics

Disease

14	Body Weight (Weight, Body) 01/2021 - 03/2003
13	Inflammation (Inflammations) 01/2022 - 02/2010
12	Type 2 Diabetes Mellitus (MODY) 12/2021 - 05/2010
11	Neoplasms (Cancer) 08/2013 - 02/2002
10	Diabetes Mellitus 01/2021 - 02/2005
8	Obesity 12/2021 - 03/2016
8	Insulin Resistance 07/2021 - 05/2007
8	Hyperplasia 01/2016 - 11/2002
7	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 06/2022 - 06/2012
7	Hyperglycemia 01/2021 - 02/2008
6	Kidney Diseases (Kidney Disease) 01/2022 - 05/2007
6	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2022 - 11/2013
6	Colorectal Neoplasms (Colorectal Cancer) 05/2015 - 03/2004
5	Carcinogenesis 01/2018 - 02/2002
5	Adenoma (Adenomas) 05/2015 - 02/2002
5	Juvenile gout 04/2014 - 11/2009
4	Infections 12/2017 - 08/2004
3	Heart Failure 01/2022 - 12/2018
3	Glucose Intolerance 07/2021 - 05/2010
3	Hypertrophy 01/2021 - 11/2002
3	Permanent Neonatal Diabetes Mellitus 01/2021 - 05/2013
3	Genetic Predisposition to Disease (Genetic Predisposition) 01/2020 - 08/2007
3	Non-alcoholic Fatty Liver Disease 01/2020 - 01/2013
3	Fibrosis (Cirrhosis) 01/2016 - 12/2012
3	Muscular Dystrophies (Muscular Dystrophy) 01/2016 - 07/2003
3	Osteoporosis 01/2012 - 02/2008
3	Colonic Neoplasms (Colon Cancer) 05/2009 - 01/2004
2	Inborn Genetic Diseases (Disease, Hereditary) 11/2021 - 01/2019
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2021 - 03/2016
2	Laron Syndrome (Syndrome, Laron) 07/2021 - 01/2018
2	Fatty Liver 01/2021 - 01/2017
2	Hyperaldosteronism (Conn Syndrome) 12/2020 - 01/2011
2	Hemorrhage 10/2020 - 12/2005
2	Muscle Weakness 09/2020 - 11/2013
2	Ulcerative Colitis 01/2020 - 05/2018
2	Pain (Aches) 01/2019 - 04/2016
2	Reperfusion Injury 01/2017 - 11/2013
2	Pancreatitis 04/2016 - 04/2010
2	Renal Insufficiency (Renal Failure) 03/2016 - 01/2014
2	Thrombotic Microangiopathies 01/2016 - 05/2015
2	Edema (Dropsy) 01/2016 - 04/2010
2	Bartter Syndrome (Syndrome, Bartter) 08/2014 - 06/2010
2	Autoimmune Diseases (Autoimmune Disease) 08/2013 - 01/2013

Drug/Important Bio-Agent (IBA)

15	Insulin (Novolin)FDA Link 07/2021 - 02/2005
14	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2004
11	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 05/2010
8	Insulin-Like PeptidesIBA 01/2021 - 03/2004
7	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 01/2018 - 01/2005
7	Urea (Carbamide)FDA LinkGeneric 08/2017 - 01/2005
6	DystrophinIBA 01/2022 - 07/2003
6	ProteomeIBA 09/2020 - 01/2016
6	CholesterolIBA 10/2018 - 01/2005
6	UromodulinIBA 01/2017 - 11/2009
5	BetacellulinIBA 08/2012 - 12/2005
4	Biomarkers (Surrogate Marker)IBA 12/2019 - 08/2012
4	LipidsIBA 01/2017 - 11/2009
4	Insulin-Like Growth Factor II (Somatomedin A)IBA 01/2007 - 02/2002
3	AldosteroneIBA 12/2020 - 08/2009
3	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2013
3	Blood Glucose (Blood Sugar)IBA 01/2020 - 05/2007
3	CytokinesIBA 01/2020 - 02/2010
3	IronIBA 01/2020 - 05/2007
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020 - 02/2002
3	Triglycerides (Triacylglycerol)IBA 10/2018 - 11/2009
3	Messenger RNA (mRNA)IBA 12/2017 - 02/2005
3	LectinsIBA 12/2017 - 01/2004
3	Growth Hormone (Somatotropin)IBA 03/2016 - 06/2004
3	ErbB Receptors (EGF Receptor)IBA 12/2013 - 08/2008
3	LigandsIBA 12/2013 - 02/2010
3	Laminin ReceptorsIBA 05/2009 - 02/2004
2	Mitochondrial DNA (mtDNA)IBA 01/2022 - 01/2021
2	AcidsIBA 12/2019 - 01/2016
2	Phosphatidylcholines (Phosphatidylcholine)IBA 12/2019 - 12/2012
2	CollagenIBA 12/2019 - 08/2013
2	EnzymesIBA 01/2019 - 09/2009
2	Hormones (Hormone)IBA 01/2019 - 10/2014
2	Pharmaceutical PreparationsIBA 10/2018 - 01/2017
2	Nonesterified Fatty Acids (NEFA)IBA 10/2018 - 11/2009
2	Streptozocin (Streptozotocin)FDA Link 01/2018 - 01/2016
2	Dextrans (Dextran)FDA Link 01/2018 - 01/2016
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2018 - 01/2016
2	Metformin (Glucophage)FDA LinkGeneric 01/2018 - 01/2015
2	Phospholipases (Phospholipase)IBA 01/2018 - 05/2011
2	BezafibrateIBA 01/2017 - 01/2016
2	AntibodiesIBA 01/2017 - 05/2008
2	Retinaldehyde (Retinal)IBA 01/2017 - 12/2005
2	CeruletideIBA 04/2016 - 04/2010
2	OxazoloneIBA 01/2016 - 01/2013
2	Complement System Proteins (Complement)IBA 01/2016 - 02/2008
2	IncretinsIBA 01/2016 - 05/2010
2	CateninsIBA 05/2015 - 11/2012
2	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 02/2015 - 12/2013
2	Member 1 Solute Carrier Family 12IBA 08/2014 - 06/2010
2	Uric Acid (Urate)IBA 10/2013 - 11/2009
2	ATP-Binding Cassette Transporters (ABC Transporters)IBA 08/2013 - 12/2012

Therapy/Procedure

8	Therapeutics 11/2021 - 05/2008
7	Transplantation 06/2022 - 01/2016
5	Heterologous Transplantation (Xenotransplantation) 11/2021 - 01/2016
2	Heart Transplantation (Grafting, Heart) 01/2021 - 12/2018
2	Islets of Langerhans Transplantation 05/2013 - 06/2012